The question seems to imply whether or not the principle of cause-and-effect occurs at all times.
In this case, the answer is, of course,
yes.
All things happen because something else caused it,
the one exception being, of course, and necessarily,
the Preeminent One,
who needs not cause, but who is Cause Itself. 
And yet, when we ask this question from the depths of our souls, it begs a different question — one of significance.
We long to know not so much that the events of our lives have logical cause, but whether the cumulative events of our lives,
that is,
the paths our lives take,
have any rhyme or reason at all,
and to what extent.
We want to know that our lives matter.
We want reassurance that we made the right decision.
We want solace in the thought that a significant life could be changed drastically by what seemed like
an accident,
or an anomaly that never should have happened.
For the past four years of my life, I have found fault in the idea of fate — that my life has a set path.
This, of course, was mainly my view of how divine sovereignty interacts with human free will.
Even earlier this year, I delved into a heated argument with a friend about whether or not God has a plan for our lives. The conversation centered upon the idea of our selection of a marriage partner (in a hemisphere in which the decision fortunately and unfortunately belongs to us).
I’ve witnessed couples and individuals scarred by the idea that, in a static way,
people are made for each other,
as if they were manufactured,
packaged,
and shipped ready and complete to their complement,
when really,
a relationship requires constant evolution, repentance, and evaluation,
and no single person is another’s full complement,
but that couple exists within society,
and their marriage is held together by and sustained for the purpose of its Third Member,
the Trinity Himself.
Regardless, in attempt to avoid this doctrine (the packed-people one, that is),
I began to believe that God’s will took a primarily spiritual rather than a physiological form in the world. I had honestly become disillusioned with my life’s course, so I began to believe God didn’t have a specific course for my job, my living situation, or another physical choice, just that I was generally supposed to love people and honor God no matter where I was.
In living this way, though, the daily tasks of my life lost any semblance of meaning they once had. Because, after all, I didn’t need to be here. God could use me somewhere else, or replace me at any time. It didn’t matter what man I married, as long as I fulfilled my duties to him and to God. It didn’t matter what I did with my time, as long as I upheld my responsibilities to company and state. This was all vanity, though, and my life lacked any romance it was once intended to have.

Yet, to my relief, upon being recently reminded of God’s intentional plan for human history,
including prophecies about events in world history, and the times and sequences in which they took place,
I reneged on my incomplete worldview.

Yes, the summation of the law and the prophets is to “Love the Lord” with everything and to “love thy neighbor as thyself,”
but this does, indeed,
take a historical and physical form.
In Christ, we are free from the law of sin and death,
and yet, at the current time I am led to believe that God intends for this to manifest itself in a specific, physical way.
That is, when one makes a life-altering decision, that takes them either to a new location or sphere of influence,
God’s hand is indeed in it,
and, indeed,
the geographical and historical direction of daily human life matters to our sovereign Lord.
If God is intentional in the way He transforms our hearts internally,
surely is He not also intentional with how He transforms our world?
Our culture?
Our communities?
Our cities?
Our workplaces?
I am led to believe that God is very meticulous in moving people to their proper places,
for “it is the Lord who builds His church,”
and that, even when we are unaware of His plan —
and assuredly, even when we disbelieve His intentionality —
it is at work in our world, in every corner.
What joy and freedom that brings!
Surely the sovereign Lord is more intentional about my own level of intentionality than I am.
Even when I am not intentional in my life’s direction,
the Lord God intentionally allows my lack of intentionality to occur,
and in so doing,
“works out all things for His good purpose.”
And this is a great comfort.
And therefore, equipped with this perspective I now have by God’s grace,
in the present, I will live intentionally,
just as He is intentional,
choosing to believe
that everything happens for a reason.

Call me an existentialist if you must. But unlike the existentialists, I have a reason to seek reason,
for everything has a Cause.